Highlighted Publications @ MedPub Scientific Communications
Nalbandian A, Dettin L, Dym M, Ravindranath N. Expression of vascular endothelial growth factor receptors during male germ cell differentiation in the mouse. Biol Reprod. 2003 Sep;69(3):985-94. doi: 10.1095/biolreprod.102.013581. Epub 2003 May 28. PMID: 12773425. https://pubmed.ncbi.nlm.nih.gov/12773425/
Nalbandian A, Djakiew D. The p75(NTR) metastasis suppressor inhibits urokinase plasminogen activator, matrix metalloproteinase-2 and matrix metalloproteinase-9 in PC-3 prostate cancer cells. Clin Exp Metastasis. 2006;23(2):107-16. doi: 10.1007/s10585-006-9009-y. Epub 2006 Aug 16. PMID: 16912916. https://pubmed.ncbi.nlm.nih.gov/16912916/
Nalbandian A, Donkervoort S, Dec E, Badadani M, Katheria V, Rana P, Nguyen C, Mukherjee J, Caiozzo V, Martin B, Watts GD, Vesa J, Smith C, Kimonis VE. The multiple faces of valosin-containing protein-associated diseases: inclusion body myopathy with Paget’s disease of bone, frontotemporal dementia, and amyotrophic lateral sclerosis. J Mol Neurosci. 2011 Nov;45(3):522-31. doi: 10.1007/s12031-011-9627-y. Epub 2011 Sep 3. PMID: 21892620. https://pubmed.ncbi.nlm.nih.gov/21892620/
Nalbandian A, Ghimbovschi S, Radom-Aizik S, Dec E, Vesa J, Martin B, Knoblach S, Smith C, Hoffman E, Kimonis VE. Global gene profiling of VCP-associated inclusion body myopathy. Clin Transl Sci. 2012 Jun;5(3):226-34. doi: 10.1111/j.1752-8062.2012.00407.x. Epub 2012 Apr 4. PMID: 22686199; PMCID: PMC3375869. https://pubmed.ncbi.nlm.nih.gov/22686199/
Nalbandian A, Llewellyn KJ, Badadani M, Yin HZ, Nguyen C, Katheria V, Watts G, Mukherjee J, Vesa J, Caiozzo V, Mozaffar T, Weiss JH, Kimonis VE. A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse. Muscle Nerve. 2013 Feb;47(2):260-70. doi: 10.1002/mus.23522. Epub 2012 Nov 21. PMID: 23169451; PMCID: PMC3556223. https://pubmed.ncbi.nlm.nih.gov/23169451/
Nalbandian A, Llewellyn KJ, Gomez A, Walker N, Su H, Dunnigan A, Chwa M, Vesa J, Kenney MC, Kimonis VE. In vitro studies in VCP-associated multisystem proteinopathy suggest altered mitochondrial bioenergetics. Mitochondrion. 2015 May;22:1-8. doi: 10.1016/j.mito.2015.02.004. Epub 2015 Feb 25. PMID: 25724235; PMCID: PMC7105354. https://pubmed.ncbi.nlm.nih.gov/25724235/
Nalbandian A, Llewellyn KJ, Kitazawa M, Yin HZ, Badadani M, Khanlou N, Edwards R, Nguyen C, Mukherjee J, Mozaffar T, Watts G, Weiss J, Kimonis VE. The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology. PLoS One. 2012;7(9):e46308. doi: 10.1371/journal.pone.0046308. Epub 2012 Sep 28. PMID: 23029473; PMCID: PMC3460820. https://pubmed.ncbi.nlm.nih.gov/23029473/
Nalbandian A, Llewellyn KJ, Nguyen C, Monuki ES, Kimonis VE. Targeted excision of VCP R155H mutation by Cre-LoxP technology as a promising therapeutic strategy for valosin-containing protein disease. Hum Gene Ther Methods. 2015 Feb;26(1):13-24. doi: 10.1089/hgtb.2014.096. PMID: 25545721; PMCID: PMC4337464. https://pubmed.ncbi.nlm.nih.gov/25545721/
Nalbandian A, Llewellyn KJ, Nguyen C, Yazdi PG, Kimonis VE. Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy. PLoS One. 2015 Apr 17;10(4):e0122888. doi: 10.1371/journal.pone.0122888. PMID: 25884947; PMCID: PMC4401571. https://pubmed.ncbi.nlm.nih.gov/25884947/
Nalbandian A, Nguyen C, Katheria V, Llewellyn KJ, Badadani M, Caiozzo V, Kimonis VE. Exercise training reverses skeletal muscle atrophy in an experimental model of VCP disease. PLoS One. 2013 Oct 9;8(10):e76187. doi: 10.1371/journal.pone.0076187. PMID: 24130765; PMCID: PMC3794032. https://pubmed.ncbi.nlm.nih.gov/24130765/
Nalbandian A, Pang AL, Rennert OM, Chan WY, Ravindranath N, Djakiew D. A novel function of differentiation revealed by cDNA microarray profiling of p75NTR-regulated gene expression. Differentiation. 2005 Oct;73(8):385-96. doi: 10.1111/j.1432-0436.2005.00040.x. PMID: 16316409. https://pubmed.ncbi.nlm.nih.gov/16316409/
Badadani M, Nalbandian A, Watts GD, Vesa J, Kitazawa M, Su H, Tanaja J, Dec E, Wallace DC, Mukherjee J, Caiozzo V, Warman M, Kimonis VE. VCP associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease. PLoS One. 2010 Oct 5;5(10):e13183. doi: 10.1371/journal.pone.0013183. PMID: 20957154; PMCID: PMC2950155. https://pubmed.ncbi.nlm.nih.gov/20957154/
Dec E, Rana P, Katheria V, Dec R, Khare M, Nalbandian A, Leu SY, Radom-Aizik S, Llewellyn K, BenMohamed L, Zaldivar F, Kimonis V. Cytokine profiling in patients with VCP-associated disease. Clin Transl Sci. 2014 Feb;7(1):29-32. doi: 10.1111/cts.12117. Epub 2013 Oct 3. PMID: 24119107; PMCID: PMC4057603. https://pubmed.ncbi.nlm.nih.gov/24119107/
Ferrari V, Cristofani R, Cicardi ME, Tedesco B, Crippa V, Chierichetti M, Casarotto E, Cozzi M, Mina F, Galbiati M, Piccolella M, Carra S, Vaccari T, Nalbandian A, Kimonis V, Fortuna TR, Pandey UB, Gagliani MC, Cortese K, Rusmini P, Poletti A. Pathogenic variants of Valosin-containing protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells. Neuropathol Appl Neurobiol. 2022 Aug;48(5):e12818. doi: 10.1111/nan.12818. Epub 2022 May 15. PMID: 35501124; PMCID: PMC10588520. https://pubmed.ncbi.nlm.nih.gov/35501124/
Gerling A, Leu SY, Morton AJ, Echegoyen J, Nalbandian A, Lingua RW. Reliability and application variability of a commercially available infrared videonystagmography unit. J Pediatr Ophthalmol Strabismus. 2015 Mar-Apr;52(2):114-8. doi: 10.3928/01913913-20150114-04. Epub 2015 Jan 21. Erratum in: J Pediatr Ophthalmol Strabismus. 2015 May-Jun;52(3):167. doi: 10.3928/01913913-20150427-11. PMID: 25608282; PMCID: PMC4725705. https://pubmed.ncbi.nlm.nih.gov/25608282/
Lieberman LA, Mizui M, Nalbandian A, Bossé R, Crispín JC, Tsokos GC. Complement receptor of the immunoglobulin superfamily reduces murine lupus nephritis and cutaneous disease. Clin Immunol. 2015 Oct;160(2):286-91. doi: 10.1016/j.clim.2015.05.006. Epub 2015 May 16. PMID: 25988858. https://pubmed.ncbi.nlm.nih.gov/25988858/
Lingua RW, Liu CY, Gerling A, Zhang Z, Nalbandian A. Myectomy of the Extraocular Muscles Without Reattachment as a Surgical Treatment for Horizontal Nystagmus. J Pediatr Ophthalmol Strabismus. 2016 May 1;53(3):156-66. doi: 10.3928/01913913-20160302-01. PMID: 27224950. https://pubmed.ncbi.nlm.nih.gov/27224950/
Llewellyn KJ, Nalbandian A, Gomez A, Wei D, Walker N, Kimonis VE. Administration of CoQ10 analogue ameliorates dysfunction of the mitochondrial respiratory chain in a mouse model of Angelman syndrome. Neurobiol Dis. 2015 Apr;76:77-86. doi: 10.1016/j.nbd.2015.01.005. Epub 2015 Feb 12. Erratum in: Neurobiol Dis. 2015 Jun;78():56. PMID: 25684537. https://pubmed.ncbi.nlm.nih.gov/25684537/
Llewellyn KJ, Nalbandian A, Jung KM, Nguyen C, Avanesian A, Mozaffar T, Piomelli D, Kimonis VE. Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease. Hum Mol Genet. 2014 Mar 1;23(5):1333-44. doi: 10.1093/hmg/ddt523. Epub 2013 Oct 24. PMID: 24158850; PMCID: PMC3919004. https://pubmed.ncbi.nlm.nih.gov/24158850/
Llewellyn KJ, Nalbandian A, Weiss LN, Chang I, Yu H, Khatib B, Tan B, Scarfone V, Kimonis VE. Myogenic differentiation of VCP disease-induced pluripotent stem cells: A novel platform for drug discovery. PLoS One. 2017 Jun 2;12(6):e0176919. doi: 10.1371/journal.pone.0176919. PMID: 28575052; PMCID: PMC5456028. https://pubmed.ncbi.nlm.nih.gov/28575052/
Llewellyn KJ, Walker N, Nguyen C, Tan B, BenMohamed L, Kimonis VE, Nalbandian A. A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy. PLoS One. 2015 Jul 2;10(7):e0131995. doi: 10.1371/journal.pone.0131995. PMID: 26134519; PMCID: PMC4489713. https://pubmed.ncbi.nlm.nih.gov/26134519/
Maducdoc MM, Haider A, Nalbandian A, Youm JH, Morgan PV, Crow RW. Visual consequences of electronic reader use: a pilot study. Int Ophthalmol. 2017 Apr;37(2):433-439. doi: 10.1007/s10792-016-0281-9. Epub 2016 Aug 5. PMID: 27495950; PMCID: PMC5929099. https://pubmed.ncbi.nlm.nih.gov/27495950/
Minckler DS, Brown DJ, Nalbandian A, Suh DW. Amyloid Precursor Protein in Abusive Head Trauma Suspects. Am J Ophthalmol. 2022 Aug;240:58-66. doi: 10.1016/j.ajo.2022.02.018. Epub 2022 Mar 2. PMID: 35247337. https://pubmed.ncbi.nlm.nih.gov/35247337/
Minckler DS, Brown DJ, Nalbandian A, Suh DW. Amyloid Precursor Protein in Abusive Head Trauma Suspects. Am J Ophthalmol. 2022 Aug;240:58-66. doi: 10.1016/j.ajo.2022.02.018. Epub 2022 Mar 2. PMID: 35247337. https://pubmed.ncbi.nlm.nih.gov/35247337/
Modica-Napolitano JS, Nalbandian R, Kidd ME, Nalbandian A, Nguyen CC. The selective in vitro cytotoxicity of carcinoma cells by AZT is enhanced by concurrent treatment with delocalized lipophilic cations. Cancer Lett. 2003 Jul 30;198(1):59-68. doi: 10.1016/s0304-3835(03)00274-x. PMID: 12893431. https://pubmed.ncbi.nlm.nih.gov/12893431/
Salimiaghdam N, Singh L, Schneider K, Nalbandian A, Chwa M, Atilano SR, Bao A, Kenney MC. Potential adverse effects of ciprofloxacin and tetracycline on ARPE-19 cell lines. BMJ Open Ophthalmol. 2020 Jul 21;5(1):e000458. doi: 10.1136/bmjophth-2020-000458. PMID: 32724857; PMCID: PMC7375423. https://pubmed.ncbi.nlm.nih.gov/32724857/
Shamirian S, Nalbandian A, Khare M, Castellani R, Kim R, Kimonis VE. Early-onset Alzheimers and cortical vision impairment in a woman with valosin-containing protein disease associated with 2 APOE ε4/APOE ε4 genotype. Alzheimer Dis Assoc Disord. 2015 Jan-Mar;29(1):90-3. doi: 10.1097/WAD.0b013e318298e54f. PMID: 23715207. https://pubmed.ncbi.nlm.nih.gov/23715207/
Weiss L, Jung KM, Nalbandian A, Llewellyn K, Yu H, Ta L, Chang I, Migliore M, Squire E, Ahmed F, Piomelli D, Kimonis V. Ceramide contributes to pathogenesis and may be targeted for therapy in VCP inclusion body myopathy. Hum Mol Genet. 2021 Feb 25;29(24):3945-3953. doi: 10.1093/hmg/ddaa248. Erratum in: Hum Mol Genet. 2024 May 18;33(11):1020. doi: 10.1093/hmg/ddae069. PMID: 33410456; PMCID: PMC8485215. https://pubmed.ncbi.nlm.nih.gov/33410456/
Yazdi PG, Su H, Ghimbovschi S, Fan W, Coskun PE, Nalbandian A, Knoblach S, Resnick JL, Hoffman E, Wallace DC, Kimonis VE. Differential gene expression reveals mitochondrial dysfunction in an imprinting center deletion mouse model of Prader-Willi syndrome. Clin Transl Sci. 2013 Oct;6(5):347-55. doi: 10.1111/cts.12083. Epub 2013 Jul 29. PMID: 24127921; PMCID: PMC3815468. https://pubmed.ncbi.nlm.nih.gov/24127921/